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KMID : 0364820200560030340
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Korean Journal of Microbiology
2020 Volume.56 No. 3 p.340 ~ p.342
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Complete genome sequence of multidrug-resistant Aeromonas hydrophila strain KN-Mc-1R2 isolated from the wild nutria (Myocastor coypus) in Korea
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Lim Se-Ra
Lee Do-Hun
Kim Young-Chae
Park Seon-Young
Kwon Hye-Min
Han Jee-Eun
Kim Ji-Hyung
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Abstract
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Aeromonas hydrophila, which is originally known as pathogens of cold-blooded animals, is presently posing serious threats to public health due to its zoonotic potential and resistance to commercial antibiotics. Herein, we present the complete genome of the multidrug-resistant A. hydrophila strain KNMc- 1R2 isolated from the wild nutria captured in Korea. The sequenced genome of strain KN-Mc-1R2 was 4,911,246 bp long with a G + C content of 61.0%, but without a plasmid.
Genomic analysis showed that the isolate encoded several virulence-associated genes including multiple enterotoxins in the genus Aeromonas and three genetic determinants related to the resistance on β-lactam antimicrobials. Based on these results, A. hydrophila isolated from the wild nutria can cause potential zoonotic infections leading to antimicrobial treatment failure in humans. The genome of A. hydrophila strain KNMc- 1R2 may help understand the potential risk factors in the genus of wild mammal origin and develop control strategies against its clinical infections.
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KEYWORD
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Aeromonas hydrophila, antibiotic resistance, environmental origins, zoonotic potential
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